Protein Family Clustering for Structural Genomics
نویسندگان
چکیده
منابع مشابه
Protein family clustering for structural genomics.
A major goal of structural genomics is the provision of a structural template for a large fraction of protein domains. The magnitude of this task depends on the number and nature of protein sequence families. With a large number of bacterial genomes now fully sequenced, it is possible to obtain improved estimates of the number and diversity of families in that kingdom. We have used an automated...
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The CATH database of protein domain structures (http://www.biochem.ucl.ac.uk/bsm/cath_new) currently contains 34 287 domain structures classified into 1383 superfamilies and 3285 sequence families. Each structural family is expanded with domain sequence relatives recruited from GenBank using a variety of efficient sequence search protocols and reliable thresholds. This extended resource, known ...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2005
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2005.08.058